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Revolution® Topical Solution for Cats
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Revolution is a prescription topical medicine for cats. It helps prevent heartworm disease, kills fleas, and treats ear mites and certain intestinal worms. You can order as a cash-pay customer without insurance.
What Revolution Is and How It Works
Revolution® (selamectin) is a monthly parasiticide for cats 8 weeks of age and older. It targets fleas, prevents heartworm disease, treats ear mites, and controls roundworm and hookworm infections in cats. This service supports US delivery from Canada so your cat’s prevention stays on schedule.
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After a single spot-on application to the skin, the solution spreads over the coat and is absorbed through the skin. It acts on the parasites’ nervous system, which can kill adult fleas, stop flea reproduction, and prevent heartworm larvae from developing. It also treats Otodectes ear mites and helps control Toxocara cati and Ancylostoma tubaeforme in cats. Use only as directed on the veterinary label.
Who It’s For
This treatment is for healthy cats and kittens 8 weeks of age and older within the labeled weight ranges. Revolution for Cat is commonly chosen for cats needing broad monthly parasite prevention, including flea control and heartworm prevention, with added ear mite and intestinal worm coverage. Cats that are ill, underweight, or debilitated may not be good candidates; a veterinarian should assess suitability. If you need other cat therapies, browse our Pet Medications.
Dosage and Usage
Apply once every month, using the tube size matched to your cat’s weight. Part the hair at the base of the neck until skin is visible. Empty the entire tube onto the skin in a single spot. Do not massage in. Avoid contact with the application site until it is dry. Selamectin Cat Topical Solution must be used exactly as prescribed. Do not use on dogs or other animals unless instructed by a veterinarian. If your cat has long hair, take extra care to place the dose directly on skin, not fur.
For bathing and grooming, follow label directions. Do not apply to wet hair. Avoid shampooing right before dosing. Many labels note the product remains effective after the application site has dried; check the package insert for timing details. Prevent ingestion by keeping treated cats separated until the site is dry.
Strengths and Forms
This medicine is supplied as single-use, spot-on tubes sized by weight. For cats, commonly available presentations include tubes intended for kittens and small cats (up to 5 lb) and for larger cats (5.1–15 lb). These deliver selamectin doses that align with label-specified mg per kg. Multipacks may be available; availability can vary by lot and dispensing pharmacy.
Missed Dose and Timing
If a monthly dose is missed, give the next dose when remembered and resume the monthly schedule. Do not double up to make up a missed application. For substantial gaps in heartworm prevention, speak with a veterinarian about next steps. Mark a calendar or set a reminder to keep a steady monthly cadence.
Storage and Travel Basics
Store the tubes at room temperature as directed on the label. Keep in the original foil packaging until use. Protect from heat, open flame, and direct sunlight; the contents are flammable until dry. Keep out of reach of children and other pets. For travel, keep tubes in a sealed pouch, pack your prescription label or a copy of your vet’s directions, and place liquids per airline rules. You can store this product securely and apply it during trips if a monthly dose falls while you travel.
Benefits
This medicine provides broad parasite control in one monthly dose. It kills adult fleas and prevents flea reproduction. It prevents heartworm disease when given every month as labeled. It treats ear mites, which can reduce scratching and head shaking. It also controls common roundworms and hookworms in cats. Use a veterinarian-approved dewormer if your pet needs additional tapeworm treatment; see our guide to Droncit For Cats.
For ear mite control specifically, the labeled Revolution Ear Mite Treatment for Cats can clear infestations when used as directed. Always confirm the diagnosis and follow your veterinarian’s plan for rechecks.
Side Effects and Safety
- Temporary hair clumping or mild hair loss at the application site
- Mild itching or redness where applied
- Transient lethargy or reduced appetite
- Drooling or lip-smacking if the product is licked before it dries
- Occasional digestive upset
Serious reactions are uncommon but can include muscle tremors, incoordination, or signs of hypersensitivity. Keep the product away from your cat’s mouth and eyes. Use only the tube size matched to your cat’s weight. If your cat is underweight, debilitated, or has a known sensitivity to macrocyclic lactones, discuss suitability with a veterinarian before use. Report concerning signs to a veterinary professional.
Drug Interactions and Cautions
Tell your veterinarian about all medicines, supplements, and parasite preventives your cat receives. Caution is advised if combining multiple parasite treatments in the same month unless directed by a veterinarian. Use care alongside topical steroids on the application site to reduce skin irritation. When antibiotics are needed for unrelated issues, your vet might choose options such as those discussed in Cephalexin For Cats or allergy therapies like Atopica Cats. Never change dosing on your own; follow the label and your vet’s guidance.
What to Expect Over Time
After proper application, flea activity typically decreases as the active ingredient distributes and takes effect. Ear mite signs can improve with labeled use and rechecks if needed. Intestinal worm control follows the schedule directed by your veterinarian. With consistent monthly use, Revolution for Cats Heartworm Prevention helps prevent heartworm disease. Maintain the same monthly timing each cycle for steady protection.
Compare With Alternatives
If your cat needs added tick coverage or a different spectrum, your veterinarian may suggest another approved topical from our catalog. Two options to consider are Nexgard Combo for broad parasite control in cats and Capstar For Cat Dog for rapid, short-term flea knockdown. Selection depends on your cat’s age, weight, indoor/outdoor exposure, and region.
Pricing and Access
See Revolution for Cats Price on the product page and compare pack sizes before checkout. Orders are dispensed by licensed pharmacies, and fulfillment Ships from Canada to US once your prescription is verified. Create an account to view current pricing and availability, then upload your prescription at checkout. For seasonal offers, visit our Promotions page. We use encrypted checkout to protect your information.
Availability and Substitutions
Supply can vary by strength, pack size, and manufacturer lot. If an item is temporarily unavailable, your prescriber may recommend a suitable alternative with similar coverage. If you need selamectin-based therapy today, you can Buy Selamectin for Cats when your veterinarian approves that option. Always use the cat-appropriate tube size and follow the label.
Patient Suitability and Cost-Saving Tips
Cats who tolerate topicals and need combined flea, heartworm, and ear mite coverage are often good candidates. Cats with known sensitivity to macrocyclic lactones, or those who are debilitated, may require a different plan. To manage costs, consider multi-month packs when prescribed, align refills with routine vet visits, and set reminders to avoid late orders. You can place your order early to prevent gaps in prevention, and you can store unopened tubes for future months per label directions.
Questions to Ask Your Clinician
- Is my cat in the correct weight range for this tube size?
- How should I time the dose with bathing or grooming?
- Do we need follow-up checks for ear mites or intestinal worms?
- Should I combine this with any tick control based on local risk?
- What signs of irritation or sensitivity should I watch for after dosing?
- How long should my cat stay separated from other pets after application?
Authoritative Sources
Manufacturer Product InformationFDA CVM FOI SummaryHealth Canada DPD Listing
Pricing and Access
Ready to proceed? Upload your prescription and complete checkout for prompt, express shipping with US shipping from Canada. This product is shelf-stable; temperature-controlled handling when required applies to select items. Always follow your veterinarian’s directions.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
How is the topical applied?
Apply once monthly to the skin at the base of the neck. Part the hair until skin is visible, then empty the full tube onto a single spot. Do not massage it in, and keep your cat away from other pets until the site is dry. Avoid contact with your hands, eyes, or mouth. Wash your hands after use. Use only the tube size labeled for your cat’s weight and follow the veterinary label for timing around bathing and grooming.
Can kittens use selamectin?
Kittens can receive this therapy from 8 weeks of age when they meet the labeled weight range. Your veterinarian will choose the correct tube size for small cats and adjust as your kitten grows. If your pet is underweight or recovering from illness, a veterinary assessment is recommended before starting or continuing therapy. Use the medicine exactly as directed and avoid mixing additional parasite products unless your vet advises it.
What if my cat licks the spot?
If a cat licks the area before it dries, you may see brief drooling or lip-smacking. Prevent access to the site by applying at the base of the skull where grooming is difficult, and keep pets separated until the application dries. If significant ingestion or unusual signs occur, contact a veterinarian. Future doses should be applied carefully to the skin with the hair parted to reduce the chance of licking.
Can I bathe my cat after dosing?
Follow the label for bathing guidance. Do not apply to wet hair and avoid bathing immediately before application. Once the application site has dried, many labels note that efficacy persists with normal grooming. If your cat needs a bath for medical reasons, ask your veterinarian about the best timing relative to the monthly dose. Always apply the solution directly to clean, dry skin for consistent performance.
Does it cover ticks?
This product provides flea control, heartworm prevention, ear mite treatment, and control of certain intestinal worms in cats. Tick protection may require a different labeled product if your veterinarian advises broader coverage. If ticks are a concern based on your region or outdoor exposure, ask your vet about adding or switching to a topical with tick activity. Use only one product at a time unless your veterinarian advises otherwise.
Is a heartworm test needed first?
Your veterinarian may recommend testing before or during preventive therapy, especially after gaps in dosing. Testing helps assess prior exposure and guides care. Continue monthly dosing as prescribed and avoid missed applications. If you miss multiple months or move to a higher-risk area, consult your veterinarian about testing and next steps. Never change your dosing schedule without professional guidance.
Can it be used with other flea products?
Combining parasite products in the same month should only be done under veterinary direction. Overlapping therapies can increase the chance of skin irritation or other side effects. If a rapid flea knockdown is required, your veterinarian may recommend a short-acting product followed by ongoing monthly prevention. Provide your vet a full list of medications, supplements, and recent treatments to check for interactions.
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