Revolution® Topical Solution for Cats

This prescription topical medicine helps protect cats against several common parasites. It is used monthly to prevent heartworm disease and control fleas, ear mites, and certain intestinal worms. This page explains how it works, who it suits, how to use it safely, and how to access it.

What Revolution Is and How It Works

Revolution® is a selamectin-based endectocide for cats. With US shipping from Canada, you can review options and compare access without insurance. CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

This medicine targets multiple parasites at approved doses. It prevents heartworm disease by killing Dirofilaria immitis larvae acquired in the previous month. It also kills adult fleas and prevents flea eggs from hatching, treats ear mite infestations, and treats or controls some intestinal roundworms and hookworms. Many pet owners use revolution topical solution for cats when a single monthly product is preferred.

Selamectin activates glutamate-gated chloride channels in susceptible parasites. This disrupts neural transmission in those organisms and leads to paralysis and death. In cats, this class has activity against fleas, ear mites, certain nematodes, and heartworm larvae.

For information on specific conditions, see related topics like Feline Flea Infestation, Feline Ear Mite Infestation, and Feline Heartworm Disease.

Who It’s For

This treatment is for cats and kittens at or above the labeled minimum age and weight, typically eight weeks of age and older. It may be considered for indoor and outdoor cats in areas where fleas or heartworm are present. It also treats ear mites; some caregivers choose it specifically for revolution ear mites coverage.

Do not use on sick, debilitated, or underweight animals unless directed by a veterinarian. Discuss use if your cat has a history of neurologic disorders or has had reactions to avermectin or milbemycin products. Breeding, pregnant, or lactating queens should be evaluated by a veterinarian before starting or continuing any parasiticide.

Dosage and Usage

Follow the prescription directions provided by your veterinarian. The medicine is applied to the skin once monthly at the recommended dose for the cat’s weight band. Part the hair at the base of the neck, apply the entire tube contents directly to clean, dry skin, and allow the site to dry. Avoid touching the area until dry.

Do not split tubes or reapply early without veterinary guidance. Keep product away from eyes and mouth, and prevent cats from licking the application site until dry. If your veterinarian has provided weight-based instructions, do not substitute other products without approval. Questions about selamectin cat dosing should be directed to your veterinary professional.

Bathing guidance can vary; consult your veterinarian if frequent bathing or grooming is expected. Ensure monthly adherence for continuous heartworm prevention and reliable flea control.

Strengths and Forms

This prescription is supplied as single-use pipettes containing selamectin in different strengths, matched to body weight. Availability can vary by pharmacy and region.

• Kittens and small cats: 15 mg per 0.25 mL tube
• Cats 5.1 to 15 lb: 45 mg per 0.75 mL tube
• Larger cats 15.1 to 22 lb: 60 mg per 1.0 mL tube

Ask your veterinarian about the best option for a growing kitten, including whether revolution for kittens is suitable as your pet’s weight changes.

Missed Dose and Timing

If a monthly dose is missed, apply a dose as soon as you remember and resume the regular monthly schedule. Keeping a consistent monthly date helps maintain protection for heartworm and external parasites. Do not double up doses to make up for missed applications. If a significant gap occurs, consult your veterinarian regarding heartworm testing before resuming.

Storage and Travel Basics

Store tubes at room temperature as directed on the label, typically below a specified maximum temperature. Keep in the original packaging, out of reach of children and pets. The solvent is flammable; keep away from heat, sparks, open flames, and sources of ignition. Do not use if the seal is broken or the tube is damaged.

For travel, carry your prescription, the labeled carton, and a list of your cat’s medicines. Pack tubes to prevent puncture or leakage, and avoid leaving them in hot vehicles. If flying, place the box in a sealed bag within your carry-on. Dispose of used tubes and caps securely so pets cannot access residues.

For additional parasite topics, you can review Feline Roundworm Infection and Feline Hookworm Infection.

Benefits

This monthly endectocide can help simplify parasite control for many households. It covers heartworm prevention, flea control, ear mite treatment, and certain intestinal worms in a single application. The treatment reduces the need for multiple separate products and can support year-round prevention plans recommended by veterinarians.

For owners prioritizing broad coverage, this approach may streamline refills and adherence. It also serves as a convenient option when a veterinarian recommends a multi-parasite plan. Some users consider it when they want a revolution cat dewormer approach alongside flea management.

Side Effects and Safety

• Application site effects: temporary hair clumping, mild redness, or localized hair loss
• Skin irritation: itching or flaking at the site
• Gastrointestinal upset: soft stool, vomiting, or drooling if licked before drying
• Behavioral changes: transient lethargy in some cats

Serious effects are uncommon but can include neurologic signs such as incoordination or tremors. If your pet shows concerning symptoms, contact a veterinarian promptly. Do not use on cats with a known hypersensitivity to selamectin or similar macrocyclic lactones. Prevent grooming of the application site until fully dry to reduce oral exposure.

Drug Interactions and Cautions

Tell your veterinarian about all flea, tick, and worm treatments your cat receives. Using multiple macrocyclic lactones or overlapping parasiticides may increase the risk of adverse effects. Caution is advised in cats with neurologic conditions or those on drugs that lower seizure threshold.

If your veterinarian recommends additional intestinal worm coverage, they may suggest a separate dewormer product alongside this medicine. In those cases, discuss timing and sequencing. Some owners seek a revolution dewormer for cats approach, but extra tapeworm coverage often requires a different class.

For educational reading on tapeworm management, see this article: Overview of Droncit for Tapeworms in Cats and Dogs.

What to Expect Over Time

With regular monthly use, you may observe fewer signs of flea activity, such as less scratching and fewer flea dirt findings. Ear mite treatment may lead to reduced head shaking and ear debris as directed by your veterinarian. Heartworm prevention is silent; there is no visible sign that larvae have been prevented, which is why adherence is emphasized.

Your veterinarian may recommend periodic checkups and testing, especially for heartworm exposure in endemic regions. Keep a simple reminder system for monthly dosing. If your cat lives with dogs or other cats, align prevention for all pets in the household to reduce reinfestation.

Compare With Alternatives

If your veterinarian recommends tick coverage in addition to fleas and heartworm prevention, they may consider a combination product. One option is Revolution Plus, which adds tick protection beyond classic coverage. Another option is Nexgard Combo, a topical that targets fleas, ticks, certain nematodes, and tapeworms. Your prescriber can help decide which spectrum best matches your cat’s risks.

Pricing and Access

Canadian pricing with US delivery from Canada may help reduce your out-of-pocket spending. You can compare the cost of revolution for cats across pack sizes and weight bands on our product pages. Check your prescription details first to ensure you choose the correct strength.

For short-term flea knockdown while you wait to start monthly prevention, discuss a fast-acting add-on like Capstar for Cat Dog with your veterinarian. For intestinal worms not covered by this class, your prescriber may suggest Profender, Milbemax, or Drontal, depending on species and parasite findings. Browse more options under Pet Medications.

Availability and Substitutions

Stock can vary by strength. If a specific tube size is unavailable, your veterinarian may recommend an alternative parasiticide with a similar or broader spectrum. Always follow the prescribed weight band and product category.

Patient Suitability and Cost-Saving Tips

This monthly treatment suits many indoor and outdoor cats, especially in regions with heartworm or flea pressure. It may not suit cats with known hypersensitivity to macrocyclic lactones or those with certain neurologic histories. A veterinary exam helps confirm whether your cat is an appropriate candidate.

To help manage costs, ask your prescriber about multi-month quantities on a single prescription. Set calendar reminders for monthly application dates. If your household has multiple pets, request synchronized refills to simplify reordering. For additional nematode or tapeworm needs, your veterinarian might consider alternatives like Interceptor Flavour Tabs or topic-specific options detailed under Feline Roundworm Infection.

Questions to Ask Your Clinician

• Weight band: Which tube size is correct today?
• Spectrum: Does my cat need added tick or tapeworm coverage?
• Co-administration: Can I use a fast-acting flea product initially?
• Bathing: How should I time baths or grooming relative to dosing?
• Testing: Should my cat be tested for heartworm before starting or resuming?
• Safety: What signs of skin or neurologic reactions should I watch for?

Authoritative Sources

For detailed, label-reviewed information, consult these official resources:

• Manufacturer’s information from Zoetis on selamectin formulations for cats; see product pages for spectrum, safety, and label use (opens in a new window).
• FDA DailyMed database with searchable prescribing information for selamectin topical solutions.
• Health Canada Drug Product Database for Canadian listings and monographs.

Ready to proceed? You can place your order with prompt, express, cold-chain shipping and temperature-controlled handling when required.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.