Aldactazide® Tablets for Hypertension

Spironolactone HCTZ is a prescription combination diuretic used to manage high blood pressure and edema from certain conditions. You can order through CanadianInsulin with US delivery from Canada for straightforward access, including options if you pay without insurance. This page explains how the medicine works, who it suits, safety points, and practical use.

What Aldactazide Is and How It Works

Aldactazide® combines spironolactone, a mineralocorticoid receptor antagonist, with hydrochlorothiazide, a thiazide diuretic. Spironolactone HCTZ helps lower blood pressure by increasing sodium and water excretion while moderating potassium loss. The spironolactone component blocks aldosterone effects, which reduces fluid retention. The thiazide component promotes mild to moderate diuresis to support sustained blood pressure control.

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order. The combination is indicated for hypertension, and for edema related to heart failure, cirrhosis, or nephrotic syndrome when a potassium-sparing effect is desired. It may reduce pill burden versus taking each medicine separately.

Who It’s For

This medicine is used in adults with hypertension when combination diuretic therapy is appropriate. It can also help manage edema associated with congestive heart failure, liver cirrhosis, or nephrotic syndrome. People with uncontrolled hyperkalemia, Addison’s disease, anuria, or severe renal impairment should not use it.

Avoid use if you are allergic to spironolactone, hydrochlorothiazide, or sulfonamide-derived medicines. Discuss use in pregnancy or while nursing with your clinician. Those on potassium supplements or other potassium-sparing agents typically require careful supervision.

Dosage and Usage

Dosing is individualized and guided by the prescribing information and your prescriber’s direction. The treatment is usually taken once daily, sometimes in divided doses, preferably in the morning to limit nighttime urination. Take consistently with or without food; if food reduces stomach upset for you, stay consistent with that approach. Monitor blood pressure, body weight, and symptoms, and follow lab testing plans for electrolytes and kidney function.

When taking spironolactone hydrochlorothiazide tablets, avoid potassium-rich salt substitutes unless your clinician approves them. Limit alcohol that can worsen dizziness or dehydration. Do not change your dose without medical guidance; consult the official label for detailed instructions.

Strengths and Forms

This medicine is supplied as oral tablets. Common presentations include 25/25 mg and 50/50 mg tablets; availability can vary by manufacturer. Some tablets may be scored. Exact strengths stocked can change by pharmacy and jurisdiction.

Typical bottle sizes differ. Your prescriber will choose the strength and quantity that align with your treatment goals.

Missed Dose and Timing

If you miss a dose, take it when remembered unless it is close to your next dose. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not double up doses. To reduce nighttime bathroom trips, schedule doses earlier in the day when possible.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excessive heat and moisture. Keep the bottle closed tightly and out of reach of children and pets. Do not store medicine in the bathroom where humidity is high. Use the original labeled container for easy identification.

When traveling, keep your medication in carry-on luggage with the pharmacy label. Bring a copy of your prescription and a medication list. Avoid leaving tablets in a parked car or near heat sources. For long trips, pack extra doses and set reminders to maintain your schedule.

Benefits

This combination can simplify therapy by combining two diuretics into one tablet. It may help maintain potassium balance relative to a thiazide alone, while still supporting blood pressure reduction. The regimen can aid edema control in select cardiac, hepatic, or renal conditions under supervision.

Side Effects and Safety

Common effects may include increased urination, dizziness or lightheadedness, low blood pressure symptoms, nausea, or headache. Muscle cramps, fatigue, or mild stomach upset can occur. Photosensitivity reactions may appear with thiazides; use sun protection.

• Electrolyte changes: hyperkalemia or hyponatremia
• Endocrine effects: breast tenderness or gynecomastia
• Dermatologic effects: rash or photosensitivity
• Gastrointestinal: nausea or vomiting
• Neurologic: dizziness or weakness

Serious risks can include significant electrolyte disturbances, dehydration, renal dysfunction, or severe allergic reactions. The potassium-sparing component can increase potassium, particularly with ACE inhibitors, ARBs, potassium supplements, or renal impairment. Thiazides may elevate uric acid and can aggravate gout, and may affect glucose control. Seek emergency care for swelling of the face, severe dizziness, fainting, or trouble breathing.

Drug Interactions and Cautions

Important interactions can occur with ACE inhibitors, ARBs, and direct renin inhibitors due to potassium and kidney effects. NSAIDs may blunt diuretic response and stress the kidneys. Lithium clearance can be reduced, raising toxicity risk. Combining with other potassium-sparing diuretics or potassium supplements requires caution.

Bile acid sequestrants can reduce absorption; spacing doses may be advised by your clinician. Corticosteroids and amphotericin B can worsen electrolyte imbalances. Alcohol, opioids, and sedatives can intensify dizziness. Review all prescriptions, over-the-counter medicines, and supplements with your clinician and pharmacist.

For background on potassium balance and why monitoring matters, see our resource on Hypokalemia vs Hyperkalemia. If you have diabetes, this article on Diabetes and Hypertension may provide additional context.

What to Expect Over Time

Blood pressure improvements may develop gradually with steady use and lifestyle measures. Edema symptoms can fluctuate based on diet, salt intake, and comorbid conditions. Regular follow-up helps adjust therapy and monitor labs. Build a routine for taking doses and checking blood pressure at home as directed.

Compare With Alternatives

Some patients may use a thiazide alone. You can review single-agent options like Hydrochlorothiazide if a prescriber recommends it. For combination therapy with another class, ACE inhibitor plus thiazide options such as Ramipril HCTZ may be appropriate when clinically indicated.

Pricing and Access

Browse current Spironolactone HCTZ price and compare pack sizes to fit your prescription. We reflect Canadian pricing with US shipping from Canada for eligible orders. See the product page for available manufacturers and quantities. For limited-time offers, visit our Promotions page.

Availability and Substitutions

Supply can vary by manufacturer and strength. If the requested item is unavailable, your prescriber may recommend a therapeutically appropriate alternative. We also carry single agents like Spironolactone and other antihypertensives such as Losartan. Ask your clinician whether generic spironolactone hctz meets your needs.

Patient Suitability and Cost-Saving Tips

Good candidates include adults who need combination diuretic therapy and can follow lab monitoring. Those with severe kidney disease, high baseline potassium, or Addison’s disease are generally not candidates. People with gout, diabetes, or photosensitivity require tailored counseling. Follow your clinician’s guidance if you are pregnant or planning pregnancy.

To save, consider multi-month fills if your prescription allows, and set refill reminders to avoid gaps. Compare strengths and pack sizes for the best per-tablet value. Ask your prescriber about non-drug measures like sodium reduction to support therapy. If searching for deals, you may look for a spironolactone hctz coupon and check our site for featured offers.

Questions to Ask Your Clinician

• Monitoring plan: how often to check potassium and kidney function
• Dose timing: best schedule to reduce nighttime urination
• Diet: sodium limits and whether to avoid potassium salt substitutes
• Combinations: safety with ACE inhibitors, ARBs, or NSAIDs
• Symptoms: what changes warrant calling the clinic
• Sun exposure: steps to lower photosensitivity risk
• Other options: when to consider single-agent or different-class therapies

Authoritative Sources

For full prescribing details, review the official FDA label on DailyMed for Aldactazide (spironolactone and hydrochlorothiazide) tablets: DailyMed Aldactazide Label. Health Canada’s Drug Product Database lists Canadian information for this combination: Health Canada DPD. For safety background on spironolactone and thiazides, consult FDA drug information resources provided for clinicians and patients: FDA Drugs.

Related reading and categories for condition-specific guidance include our pages on Hypertension, Heart Failure, Liver Cirrhosis, and Nephrotic Syndrome. You can also browse our broader Cardiovascular category for related treatments.

Ready to proceed? You can buy spironolactone hctz online through CanadianInsulin with prompt, express, temperature-controlled handling when required.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.