Trusopt® Ophthalmic Solution 2% Eye Drops

Trusopt® is a prescription dorzolamide 2% ophthalmic solution that lowers intraocular pressure in open-angle glaucoma and ocular hypertension. CanadianInsulin offers Canadian pricing on Trusopt from Canada and ships to the US, with US delivery from Canada. This page explains labeled uses, dosing, safety, and how to order online, including options without insurance.

What Trusopt® Is and How It Works

Trusopt® contains dorzolamide hydrochloride 2% (20 mg/mL). Dorzolamide is a topical carbonic anhydrase inhibitor. By inhibiting carbonic anhydrase II in the ciliary processes, it reduces aqueous humor secretion. Lower aqueous production reduces intraocular pressure, which helps protect the optic nerve over time. Trusopt eye drops are used as monotherapy or with other glaucoma medications.

CanadianInsulin connects patients with licensed Canadian pharmacies. Prescriptions are verified with your clinic before dispensing.

Who Trusopt® Is For

This medicine is indicated to reduce elevated intraocular pressure in adults with open-angle glaucoma or ocular hypertension. It can be used alone or combined with other topical agents such as beta blockers or prostaglandin analogs when additional pressure lowering is needed.

Use may be inappropriate for certain patients. Dorzolamide is a sulfonamide. Serious reactions seen with systemic sulfonamides can occur with topical dosing, although they are uncommon. Trusopt should not be used by anyone with a known hypersensitivity to any component. It is generally not recommended in severe renal impairment due to renal excretion of dorzolamide and its metabolite. Corneal edema may occur in eyes with compromised corneal endothelium. Safety in very young children has not been established. Contact lens wearers should follow labeled handling directions because the preservative can be absorbed by soft lenses. For pediatric eye topics, see our editorial on Childrens Eye Health.

Dosage and Usage

Follow the prescribing clinician and the official label. Typical labeled schedules:

• Monotherapy: Instill one drop in the affected eye or eyes three times daily.
• With a topical beta blocker: Instill one drop in the affected eye or eyes twice daily.

General administration guidance:

• Wash hands. Avoid touching the dropper tip to any surface, including the eye or eyelids.
• If using multiple ophthalmic products, wait at least 10 minutes between drops. Use gels or ointments last.
• Remove soft contact lenses before dosing. Wait 15 minutes before reinserting.
• Gentle nasolacrimal occlusion or eyelid closure for 1 to 2 minutes may reduce systemic absorption.

These directions reflect common label practices for dorzolamide ophthalmic solution 2%. When uncertain, defer to the official label.

Strengths and Forms

Commonly dispensed presentation:

• Trusopt 2% ophthalmic solution (20 mg/mL) in a multi-dose 5 mL bottle.

Availability can vary by pack size and manufacturer. Wording you may see includes Trusopt 2% eye drops, Trusopt 5 mL eye drops, Trusopt 20 mg/mL eye drops, and dorzolamide 2% eye drops. Generic dorzolamide ophthalmic solution 2% exists; formulations and bottles may differ by supplier.

Missed Dose and Timing

If a dose is missed, instill it when remembered unless it is close to the next scheduled dose. In that case, skip the missed dose and resume the regular schedule. Do not double up. Consistency helps maintain steady intraocular pressure control.

Storage and Travel Basics

Store the bottle at controlled room temperature, typically 15 to 30°C (59 to 86°F). Keep the cap tightly closed. Do not freeze. Protect from contamination and excessive heat. For travel, keep the bottle in a clean case within carry-on luggage. You can store it upright when possible and avoid leaving it in a hot car or direct sunlight.

Pen Handling and Sharps Disposal

This product is a multi-dose eye drop bottle. No needles or sharps are involved. Dispose of empty bottles in household waste according to local guidance.

Benefits

Trusopt ophthalmic solution 2% lowers intraocular pressure by reducing aqueous humor production. It can be used alone when a carbonic anhydrase inhibitor is appropriate, or added to a regimen when extra pressure reduction is needed. The drop format avoids systemic exposure typical of oral carbonic anhydrase inhibitors. Many patients appreciate the flexible dosing schedule when used with a beta blocker.

For eye health education, see our features on Diabetic Eye Disease Month and Healthy Vision Month.

Side Effects and Safety

• Common local effects: transient burning or stinging, blurred vision, eye discomfort or tearing, dry eye, superficial punctate keratitis.
• Taste disturbance (bitter or unusual taste) after dosing.
• Eyelid inflammation or conjunctivitis.
• Headache, nausea, or fatigue have been reported.

Serious reactions are uncommon but can occur, including signs of sulfonamide hypersensitivity (severe rash, swelling, shortness of breath), corneal edema in compromised corneas, or severe ocular irritation. Discontinue and seek care if severe reactions occur. Use in pregnancy or while nursing requires clinician guidance. Do not use if the solution changes color, becomes cloudy, or if the seal is broken before first use.

Drug Interactions and Cautions

Topical dorzolamide has limited systemic exposure, but interactions are still possible. Concomitant use with oral carbonic anhydrase inhibitors may increase the risk of systemic effects and is usually avoided. Caution with high-dose salicylates and other drugs that can alter acid-base balance. When combined with other glaucoma drops, separate administrations by at least 10 minutes. Contact lens wearers should remove lenses before dosing because the preservative (often benzalkonium chloride) may be absorbed by soft lenses.

What to Expect Over Time

Intraocular pressure typically begins to fall within hours of dosing and remains controlled with regular use. Ocular comfort often improves after the first few doses as the eye adapts. Pressure goals and timelines vary by patient and regimen. Ongoing monitoring by the prescribing clinic guides long-term adjustments. Trusopt 2% ophthalmic solution helps control pressure but does not reverse preexisting optic nerve damage.

Compare With Alternatives

Several approved options may be considered based on response and tolerability. A fixed-combination product like Cosopt® combines dorzolamide with timolol to simplify regimens when both agents are needed. A non-branded option, Dorzolamide Ophthalmic Solution, contains dorzolamide 2% in a generic presentation. Prostaglandin analogs, such as latanoprostene bunod, can also be used; selection depends on clinical goals and safety considerations.

Pricing and Access

CanadianInsulin lists current Trusopt price information with Canadian pricing and US delivery from Canada. You can review the dorzolamide eye drops price, compare options, and start a secure order online. Many patients look for savings without insurance when comparing Trusopt 2% eye drops and generic dorzolamide.

To check current offers, see our Promotions. Checkout uses encrypted processing. Order Trusopt online with prompt, express shipping.

Availability and Substitutions

Supply may vary by pack size and manufacturer. If this item is temporarily unavailable, a prescriber may recommend a clinically appropriate alternative. For example, a prostaglandin analog option like Vyzulta® Ophthalmic Solution may be considered when suitable. Any substitution decision rests with the prescriber.

Patient Suitability and Cost Saving Tips

Candidates include adults with open-angle glaucoma or ocular hypertension who need pressure lowering and tolerate topical therapy. Those with sulfonamide hypersensitivity, severe renal impairment, or compromised corneal endothelium need special caution or may not be candidates. Contact lens wearers can use Trusopt eye drops if they remove lenses before dosing and wait before reinsertion.

Cost-saving ideas:

• Compare Trusopt ophthalmic solution 2% pricing with generic dorzolamide 2% eye drops.
• Ask the prescriber about a two-times-daily schedule when used with a topical beta blocker, if appropriate.
• Consider multi-month supplies to reduce per-bottle costs and fewer refills.
• Set refill reminders so therapy is not interrupted.

Questions to Ask Your Clinician

• Is dorzolamide 2% eye drops suitable as monotherapy for this pressure goal?
• Should a topical beta blocker or prostaglandin analog be added now or later?
• What signs of eye irritation or allergy should prompt a recheck?
• How should bottles be rotated when using more than one ophthalmic solution?
• Are there concerns with contact lens wear and this preservative?
• What follow-up schedule is recommended to track intraocular pressure?

Authoritative Sources

• DailyMed: Trusopt
• DailyMed: Dorzolamide
• Health Canada DPD

Start your order for Trusopt with US delivery from Canada and prompt, express shipping.