Acevet 25 (Acepromazine Maleate) Injectable Solution

Acevet is a veterinary prescription sedative (a calming medicine) that contains acepromazine maleate and is used to help reduce anxiety, facilitate handling, or support pre-anesthetic management under a veterinarian’s direction. This page summarizes practical, label-aligned basics—what the injection is, how it’s commonly used in clinical settings, what to watch for, and how to store and handle a multi-dose vial safely. It also explains how our referral process works for documentation and dispensing, including options some people use without insurance. Ships from Canada to US is available for eligible prescriptions, and the details below are intended to help with informed site actions such as submitting records and preparing for safe medication handling at home or in a clinic.

What Acevet 25 Injectable Is and How It Works

Acepromazine maleate is a phenothiazine tranquilizer (a sedative class) used in veterinary medicine. It works primarily by affecting dopamine signaling in the central nervous system, which can produce calming and reduced responsiveness to environmental stimuli. The same mechanism can also contribute to lowered blood pressure and changes in temperature regulation, which is why basic monitoring is commonly discussed whenever sedatives are used.

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In practice, this type of injection may be used as part of a broader handling or peri-procedural plan rather than a stand-alone solution. Sedatives can change how an animal responds to stress, restraint, and other medications used around procedures. For broader context on common veterinary medication categories, browse the Pet Medications hub or the Pet Health collection.

Who It’s For

This medicine is intended for veterinary use when a clinician determines that sedation or tranquilization is appropriate. It is often discussed in relation to dogs and horses, but species and indications depend on the product labeling and the veterinarian’s clinical judgment. The setting may be a clinic procedure, grooming support under supervision, transport-related stress management, or pre-anesthetic preparation, depending on the case and the protocol used.

Some animals should not receive phenothiazine sedatives or may require extra caution. For example, significant cardiovascular disease, dehydration, shock, severe illness, or a history of unusual reactions to sedatives can change the risk profile. In those situations, the veterinarian may choose a different agent, adjust the overall plan, or increase monitoring. If Acevet 25 Injectable is being considered, the decision typically accounts for temperament, age, body condition, concurrent illness, and the other medications planned for the same visit.

Dosage and Usage

Dosing for acepromazine injections is individualized and should follow the official labeling and the prescriber’s instructions. In many veterinary settings, acepromazine may be administered by intramuscular (IM) or intravenous (IV) injection, with route selection guided by the procedure, the need for onset control, and safety considerations. Because sedatives can interact with anesthetics and analgesics, the full medication plan matters as much as the single drug.

Why it matters: Sedation can alter breathing, blood pressure, and temperature during handling.

Prescription details can be confirmed with the prescriber when required.

For clinics, common practical steps include documenting the concentration (mg/mL), calculating the volume in mL based on the prescribed dose, and recording the route and time given. At home, administration is usually not appropriate unless explicitly directed and taught by a veterinarian. If a pet is receiving other injections for nausea or infection at the same time, the related guides in Pet Health Articles—such as Cerenia Uses And Dosage or Cephalexin Uses And Dosage—can help with general medication literacy (not dosing decisions).

Strengths and Forms

Acevet is supplied as a sterile injectable solution with a concentration of 25 mg/mL of acepromazine maleate. It is commonly packaged as a multi-dose vial, though vial size and packaging details can vary by source and market. The product is intended for injection use in veterinary settings, and the label may describe compatible routes, handling steps, and any limitations on use.

The table below summarizes key form details without implying availability of specific vial sizes:

When comparing products, confirm that the concentration on the vial matches the prescription and the charting system. Mix-ups are more likely when multiple injectable medications are being handled during the same appointment.

Storage and Travel Basics

Follow the storage directions printed on the carton and vial label and any instructions provided by the dispensing pharmacy. In general, injectable solutions should be protected from temperature extremes, kept in their original packaging when possible, and stored where children and animals cannot access them. Avoid using a vial if the solution looks discolored, unusually cloudy, or contains visible particles—when in doubt, ask the dispensing pharmacy or the veterinarian before using it.

Quick tip: Write the first puncture date on the carton for tracking.

For travel to a clinic or barn, transport the vial in a clean container that reduces light exposure and breakage risk. Keep supplies (needles, syringes, alcohol swabs, sharps container) separate from food items. If other temperature-sensitive veterinary therapies are part of the household routine, the general handling principles in Pet Insulin Storage Tips can be a helpful reference for safe storage habits, even though insulin has different requirements than sedatives.

Side Effects and Safety

Sedatives can cause expected effects such as drowsiness, reduced coordination, and a calmer demeanor, and these effects may persist longer than anticipated in some animals. Acepromazine can also lower blood pressure and contribute to heat loss, so weakness, pale gums, unusual lethargy, or trouble staying warm may be signs that the animal needs reassessment. Some animals can show paradoxical agitation rather than calmness, particularly if they are highly stressed.

Acevet 25 Injectable should be used with caution when an animal has significant systemic disease, is very young or very old, or is taking other central nervous system depressants. Rare but serious reactions can include collapse, severe breathing difficulty, or signs consistent with a hypersensitivity reaction (for example, facial swelling or sudden hives). Treat any severe or rapidly worsening symptoms as urgent and contact a veterinary professional immediately.

Monitoring and when to seek help

Monitoring after sedation typically focuses on responsiveness, breathing pattern, gum color, temperature, and the ability to stand safely. In a clinic, staff may also track heart rate and blood pressure when indicated. At home, keep the animal in a quiet, low-stimulation area and prevent access to stairs, pools, or slippery floors until coordination is clearly normal. If vomiting, repeated collapse, uncontrolled agitation, persistent unresponsiveness, or labored breathing occurs, contact an emergency veterinary service. If sedation is part of a broader plan (for example, pain control or anti-nausea care), review the entire medication list with the veterinarian so warning signs are not missed.

Drug Interactions and Cautions

Acepromazine can have additive effects with other drugs that depress the nervous system or lower blood pressure. This includes many anesthetics, opioid pain medicines, some antihistamines, and other tranquilizers. Combining sedatives is common in veterinary protocols, but it should be planned and monitored by a veterinarian because the combined effect is not always predictable from the individual medications.

Important cautions may also apply to animals with seizure disorders, severe liver disease, severe heart disease, or dehydration, depending on the case and the label guidance. Share the full medication list with the prescriber, including flea/tick products, supplements, and any recent sedatives. For additional general reading on medication coordination in chronic conditions, resources like Managing Pet Diabetes can help with record-keeping habits that also apply to peri-procedure medication planning.

Compare With Alternatives

Veterinarians may consider other sedatives or tranquilizers based on the procedure, temperament, and health status. One common alternative class is alpha-2 agonists (for example, dexmedetomidine), which have different cardiovascular effects and reversal options. Another option may be choosing a related phenothiazine product depending on local labeling and availability. The best choice depends on the full protocol, not a single drug.

When comparing Acevet 25 Injectable to alternatives, practical differences often include onset predictability by route, degree of cardiovascular effect, and how the medicine fits into a multi-drug plan. For reference within our catalog, see Dexdomitor Vial as an example of a different sedative class, or Atravet as another veterinarian-selected option. These links are for product identification and should not be used to choose therapy without clinical guidance.

Pricing and Access

Because this is a prescription veterinary injection, access depends on a valid prescription and appropriate documentation. Some households use cash-pay options when coverage is limited, and a veterinarian may provide the required prescription details for the specific concentration and route. If you are managing multiple long-term therapies, keep a current medication list and allergy history to reduce delays in verification and dispensing.

Dispensing is completed by licensed Canadian pharmacies.

For site actions, submit the prescription information and contact details so the order can be reviewed for completeness and routed appropriately. A second option sometimes used is self-pay access without insurance, depending on the prescription and local requirements. US shipping from Canada may be available for eligible orders based on documentation and destination rules.

Authoritative Sources

For neutral background on tranquilizer classes used in veterinary medicine, see this overview from a veterinary reference: Merck Veterinary Manual: Phenothiazine tranquilizers.

For standards on anesthesia and monitoring practices in small animals, consult these clinical guidelines: AAHA anesthesia and monitoring guidelines.

To proceed on the site, provide required prescription details and request prompt, express, cold-chain shipping.

This content is for informational purposes only and is not a substitute for professional medical advice.