Baytril® (Enrofloxacin) for Dogs and Cats: Uses, Doses, Safety

What Baytril® Is and How It Works

Baytril® (enrofloxacin) is a fluoroquinolone antibiotic used in veterinary medicine. It helps treat susceptible bacterial infections in dogs and cats, including skin, soft tissue, respiratory, and urinary tract infections. Common tablet strengths include 22.7 mg, 68 mg, and 136 mg. Baytril otic is an ear medication for dogs. Baytril 100 is an injectable formulation used under veterinary direction. This page lists Baytril for sale in popular formats for clinical use.

CanadianInsulin is a prescription referral service. Prescriptions are verified with your clinic, and orders are filled by licensed Canadian pharmacies.

Enrofloxacin blocks bacterial DNA gyrase and topoisomerase IV, which prevents DNA replication. That action provides broad coverage against many gram-negative organisms and some gram-positive species. Once-daily dosing is typical for many indications, which supports adherence. Some pets respond within a few days when the pathogen is susceptible and dosing is optimized.

Baytril medication is available as flavored tablets for dogs and cats, an otic suspension for canine ear infections, and injectable solutions used by veterinarians. If you need a deeper dive on injections in cats, see Baytril Injection For Cats Uses Dosage And Safety Guide. For a broader overview, read What Is Baytril Antibiotic A Complete Guide For Pet Owners.

Dosage and Usage

• Follow the prescription from your veterinarian. Typical courses range from 5 to 14 days, depending on the site and severity of infection.
• Tablets: Dogs often receive 68 mg or 136 mg once daily based on weight. Cats are usually dosed once daily using appropriate mg/kg guidance.
• Scored tablets can be split to match the prescribed dose.
• Give tablets with a small meal if stomach upset occurs. Avoid giving with dairy or mineral supplements that can bind the drug.
• Missed dose: Give it when remembered unless it is near the next dose. Do not double dose.
• Baytril otic for dogs: Clean the ear canal as directed by your veterinarian. Shake the bottle, instill the prescribed number of drops, and gently massage the ear base.
• Baytril 100 and other injectable forms should be administered only by veterinary professionals.
• Do not stop therapy early unless your veterinarian instructs otherwise, even if signs improve.

• Storage: Keep tablets at 15–30°C (59–86°F) in a dry place. Protect from moisture and light.
• Otic suspension: Store at room temperature and keep the cap tightly closed. Do not freeze.
• Travel: Keep medication in original packaging. Carry a copy of your prescription. Avoid excessive heat during transit.
• Keep all medications out of reach of children and animals.

Benefits and Savings

Baytril antibiotic offers broad-spectrum coverage and once-daily dosing convenience. Tablets are palatable for many pets, and the otic form targets bacterial ear infections in dogs. Availability across multiple strengths, including Baytril 68mg for dogs and Baytril 136mg, helps precise dosing. Generic baytril (enrofloxacin) options may also be available when appropriate.

We work with licensed and vetted partner pharmacies to supply authentic brand medications, a broad selection, and value-focused pricing. Many customers save 60–80% vs typical U.S. prices.

Baytril medication for dogs is prescribed for susceptible skin, soft tissue, and urinary infections, including cases labeled as Baytril for dog ear infection and Baytril for dog UTI when cultures and clinical judgment support use. Enrofloxacin baytril has a long track record in small animal practice.

Side Effects and Safety

• Common effects: decreased appetite, vomiting, diarrhea, or soft stools.
• Occasional: lethargy, restlessness, or hypersensitivity reactions.
• Cats: high doses have been linked to retinal effects; dosing must be conservative.
• Growing dogs: fluoroquinolones may affect cartilage in large-breed puppies; use is typically restricted.
• Neurologic concerns: use caution in animals with seizure disorders.
• Drug interactions: antacids, iron, calcium, and sucralfate can reduce absorption; separate administration times. Theophylline and cyclosporine interactions are possible.
• Pregnancy and lactation: risk–benefit should be assessed by a veterinarian.

Serious but uncommon risks include hypersensitivity, tendon or joint issues in growing dogs, or neurologic effects. Stop the medication and contact your veterinarian if severe reactions occur. Use is regulated or restricted in some species and settings; for example, enrofloxacin use in poultry is restricted in the U.S.

Onset Time

Clinical improvement for skin or soft tissue infections may appear within 48–72 hours when the pathogen is susceptible. Urinary tract symptoms often ease within several days. Ear discomfort can start to improve within 2–3 days with appropriate cleaning and Baytril otic. Always complete the prescribed course to reduce relapse and resistance risks.

Compare With Alternatives

Clavamox® (amoxicillin/clavulanate) is a first-line option for many skin and soft tissue infections. It offers broad gram-positive coverage and some gram-negative activity, but dosing is usually twice daily.

Convenia® (cefovecin) is a long-acting injectable cephalosporin administered by veterinarians. It can be useful when oral dosing is difficult, with effects lasting up to two weeks after a single dose.

Zeniquin® (marbofloxacin) is another fluoroquinolone with similar spectrum to enrofloxacin. Dosing is often once daily, and it can be considered when culture results or tolerance favor an alternative agent.

Combination Therapy

• Ear infections: Baytril otic for dogs is often paired with proper ear cleaning and, when indicated, anti-inflammatory therapy prescribed by a veterinarian.
• Skin infections: antiseptic shampoos or topical antimicrobials can support systemic therapy.
• GI support: probiotics may be considered to help maintain normal gut flora during antibiotic courses.
• Avoid combining multiple systemic antibiotics unless culture results and veterinary guidance support it.

Patient Suitability and Cost-Saving Tips

Baytril antibiotic for dogs and cats is intended for infections caused by susceptible bacteria. It is not for viral or fungal diseases. Caution is advised in young, growing large-breed dogs, in cats that require precise dosing, and in pregnant or nursing animals. Enrofloxacin for guinea pigs and other small mammals may be used under veterinary direction; species-specific dosing and safety vary. Regulations limit use in certain birds and food-producing species.

To manage the Baytril price, consider multi-month refills when appropriate, which can reduce per-shipment costs. Tablets are scored, which may help match prescribed mg/kg needs across sizes like Baytril 68mg for dogs or Baytril 136mg under veterinary direction. If a suitable substitute exists, enrofloxacin for sale as a generic may offer additional savings. Keep reorder reminders so you never run out during a treatment course.

Authoritative Sources

Elanco Baytril Otic product information

FDA Animal Drugs database search for approved enrofloxacin labels

Health Canada Drug Product Database (DPD)

Order Baytril® from CanadianInsulin: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This material is educational and does not replace your veterinarian’s advice. Always follow your pet’s prescription and the product label.