Invokana® (Canagliflozin) Tablets for Type 2 Diabetes

What Invokana® Is and How It Works

Invokana is the brand name for canagliflozin, an SGLT2 inhibitor used in adults with type 2 diabetes. It helps lower blood sugar and supports kidney and heart health in certain patients. Many people compare options by searching invokana price, dosing, and benefits when planning care with their clinician.

CanadianInsulin is a prescription referral service. Prescriptions are verified with your clinic, and orders are filled by licensed Canadian pharmacies. We partner with licensed, vetted pharmacies to supply authentic brand medications and value-focused pricing.

Invokana works in the kidneys by blocking sodium-glucose co-transporter 2 (SGLT2). This reduces glucose reabsorption and increases urinary glucose excretion. The result is lower blood glucose, modest calorie loss, mild diuresis, and small reductions in blood pressure. Canagliflozin may also reduce the risk of major cardiovascular events and help slow kidney disease progression in adults with type 2 diabetes and albuminuria, when used as indicated.

Form and route: oral tablets in 100 mg and 300 mg strengths. Typical dosing is once daily before the first meal of the day. Your clinician may adjust the dose based on kidney function, tolerability, and treatment goals.

Dosage and Usage

• Usual starting dose: 100 mg once daily, taken before the first meal.
• Possible increase to 300 mg once daily if tolerated and kidney function allows.
• Swallow tablets whole with water. Maintain adequate hydration.
• Kidney function considerations guide dose and suitability; monitoring is routine.
• Missed dose: take the same day when remembered. If near the next dose, skip the missed dose. Do not double doses.
• When used with insulin or a sulfonylurea, a dose reduction of those agents may be considered to lower hypoglycemia risk.
• Injection is not required; Invokana is taken by mouth.

• Storage: keep tablets at 20–25°C (68–77°F). Short excursions 15–30°C (59–86°F) are acceptable.
• Store in the original container with the desiccant. Protect from moisture and heat.
• Keep out of reach of children and pets.
• Travel: carry your medication in hand luggage. Bring enough for the entire trip plus extra.
• Do not store in a bathroom. Close the cap tightly after each use.

Benefits and Savings

Clinical studies show canagliflozin lowers A1C and fasting plasma glucose, with effects that build over weeks. Many patients also see 2–4 kg of weight reduction over months, plus small decreases in blood pressure from mild diuresis. Cardiovascular and kidney benefits have been shown in adults with type 2 diabetes and established risks, when used as indicated.

Once-daily tablets make Invokana convenient for long-term management. No injections are needed, and it can be combined with metformin, GLP‑1 receptor agonists, DPP‑4 inhibitors, or basal insulin as clinically appropriate.

Many customers save 60–80% vs typical U.S. prices. See our promotions page for current offers, including any invokana coupon if available.

Side Effects and Safety

• Common: increased urination, thirst, dry mouth, constipation, nausea, dizziness, headache.
• Genital yeast infections (women and men) and urinary tract infections.
• Volume depletion or low blood pressure, especially in older adults or with diuretics.
• Electrolyte changes and a small rise in LDL cholesterol.
• Low blood sugar mainly when combined with insulin or sulfonylureas.

Serious but less common risks include ketoacidosis (can occur even with near-normal glucose), acute kidney injury, severe urinary infections (urosepsis, pyelonephritis), necrotizing fasciitis of the perineum (Fournier’s gangrene), bone fractures, and increased risk of lower-limb amputation seen in some trials. Stop and seek urgent care for symptoms of ketoacidosis (nausea, vomiting, abdominal pain, unusual fatigue, trouble breathing) or severe infection. Discuss foot care, hydration, and sick-day plans with your clinician.

Onset Time

Blood glucose changes can appear within the first 1–2 weeks, with A1C reductions continuing through 12–24 weeks as the dose stabilizes. Modest weight changes may begin within a month, with further effects over 3–6 months. Blood pressure improvements often appear within several weeks due to mild diuretic effects.

Compare With Alternatives

Other SGLT2 inhibitors include empagliflozin (brand Jardiance) and dapagliflozin. Jardiance has strong cardiovascular outcome data, and dapagliflozin is also used for glycemic control and cardiorenal protection in indicated populations. You can compare availability and strengths with Dapagliflozin and Buy Jardiance 10 25 Mg.

GLP‑1 receptor agonists such as Rybelsus® (oral semaglutide) or Trulicity® (dulaglutide) are non‑insulin options that improve glycemic control and support weight reduction. Some patients use an SGLT2 inhibitor with a GLP‑1 agent for complementary benefits when appropriate.

Combination Therapy

• Metformin plus canagliflozin is a common foundation for glucose control.
• SGLT2 inhibitor with a GLP‑1 receptor agonist can address both A1C and weight goals.
• With basal insulin, clinicians may reduce insulin dose to limit hypoglycemia.
• With a sulfonylurea, a dose reduction may lower hypoglycemia risk.
• Combination with DPP‑4 inhibitors is possible when tailored to goals.

Patient Suitability and Cost-Saving Tips

Invokana is for adults with type 2 diabetes as part of a broader plan that may include diet and activity. It is not for type 1 diabetes or diabetic ketoacidosis. Clinicians consider kidney function (eGFR), volume status, blood pressure, history of genital infections, risk of amputation, and fracture history when assessing suitability.

Hydration matters, especially for older adults, those on diuretics, or those with low blood pressure. Procedures or acute illness may require pausing therapy; practitioners provide individualized guidance on sick-day management. Discuss pregnancy and breastfeeding plans, as use later in pregnancy is generally avoided due to potential effects on the fetus.

To manage costs, many customers choose a 2–3 month supply per order and set simple reminders to reorder before running low. Compare strengths to match your prescription and avoid partial fills. Ordering together with other eligible medications can reduce per-shipment overhead.

Authoritative Sources

Manufacturer’s Invokana consumer site

Janssen Invokana Prescribing Information (U.S.)

FDA canagliflozin label and Medication Guide

Order Invokana from CanadianInsulin: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider about your specific situation.