Profender® Topical Solution for Cats

Profender® is a topical dewormer for cats and kittens that treats and controls common intestinal worms, including roundworms, hookworms, and tapeworms. With US delivery from Canada, families can access Canadian pricing on this vet‑authorized option, including those paying cash without insurance. Applied to the skin at the back of the neck, it offers single‑dose coverage designed for everyday parasite protection needs.

What Profender® Is and How It Works

At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.

Profender® combines two well‑studied anthelmintics: emodepside and praziquantel. Emodepside targets neuromuscular receptors in nematodes (roundworms and hookworms), leading to paralysis and death. Praziquantel disrupts the protective outer layer of cestodes (tapeworms), making them vulnerable to the cat’s immune and digestive processes. Because it is applied on the skin and absorbed systemically, a single dose reaches intestinal parasites without the need to give an oral tablet.

The dual‑active formula covers multiple intestinal parasites in one application and reaches adult and immature stages listed on the label. Profender works within the body rather than sitting on the coat, which is helpful for cats that groom vigorously or will not reliably swallow pills. Used as part of a broader parasite plan, Profender can complement flea control to lower the risk of tapeworm reinfection carried by fleas. For broader pet health topics and options, browse our Pet Medications.

Who Profender® Is For

Indicated for cats and kittens at least 8 weeks old and meeting the minimum weight threshold listed on the package. It is appropriate for indoor and outdoor cats at risk of intestinal parasites through flea exposure, hunting small prey, or contact with contaminated environments.

• Do not use in cats with known hypersensitivity to emodepside or praziquantel.
• Not evaluated for very young kittens or those below the lowest labeled weight range.
• Use with caution in pregnant or lactating queens; a clinician should assess risks and benefits.
• Defer treatment in severely ill or debilitated animals until stable, unless a clinician directs otherwise.
• Keep treated cats separated from other pets until the application site dries to prevent licking.

Flea prevention helps break the tapeworm cycle; many households pair deworming with a monthly topical such as the broader spectrum Revolution Plus.

Dosage and Usage

Profender is supplied in single‑use tubes sized to body weight. One full tube applied once is typically sufficient for labeled parasites; a veterinarian may recommend repeat dosing if reinfection is likely.

1. Weigh the cat to select the correct tube size.
2. Hold the tube upright, remove the cap, and puncture the seal as directed on the package.
3. Part the hair at the base of the skull on the back of the neck until skin is visible.
4. Place the tip on the skin and squeeze the entire contents directly on the skin in one spot.
5. Discard the empty tube safely, and prevent licking or grooming of the area until dry.

Do not apply to broken skin. Avoid contact with eyes and mouth. Do not massage the product into the skin; allow it to absorb naturally. Bathing or shampooing should be avoided until the application site is fully dry. Reinfection can occur in environments with fleas or prey exposure; a clinician may advise repeating treatment no sooner than a month after the initial dose.

Kittens moving onto parasite prevention can transition to flea and tick products such as Revolution For Puppies Kittens when age and weight criteria are met.

Strengths and Forms

Profender topical solution for cats is available in single‑dose tubes formulated by body‑weight ranges. Common packages include presentations for small, medium, and large cats, with tube volumes matched to labeled weight bands. Active ingredients are emodepside and praziquantel; availability may vary by pharmacy stock.

Weight‑based tubes typically cover the following ranges:

• Small cats: 2.2–5.5 lb
• Medium cats: 5.6–11 lb
• Large cats: 11.1–17.6 lb

Check the carton for the exact weight band and use only the tube size that matches the cat’s current weight.

Missed Dose and Timing

Profender is not a daily medicine. If a scheduled deworming window is missed, apply a single dose when remembered as long as the correct tube size is available and no adverse effects are present from prior use. Do not apply more than one full dose within a 30‑day period unless directed by a veterinarian. For ongoing exposure risks, clinicians often recommend periodic fecal testing and repeating treatment when parasites are detected.

Storage and Travel Basics

Store your Profender at controlled room temperature away from heat and direct sunlight. Keep tubes in the original packaging until use, and protect from puncture.

• Keep out of reach of children and other animals.
• Wash hands after handling and avoid contact with skin or eyes.
• During travel, pack your tubes in a sealed plastic bag inside your carry‑on to help prevent leaks.
• Keep away from open flame; allow the application site to dry before close contact.
• Dispose of used tubes in household trash; do not flush.

Prescription medicines may be subject to transport rules; carrying your order summary can help when traveling.

Benefits

• Broad coverage against key feline intestinal parasites, including tapeworms, roundworms, and hookworms.
• Single topical dose administered at the back of the neck; no oral tablet to swallow.
• Systemic action reaches parasites in the intestine after skin absorption.
• Convenient option for multi‑cat households and cats that resist oral medications.
• No fasting or special diet required at the time of application.
• Complements flea control to reduce tapeworm reinfection risk.

Side Effects and Safety

• Temporary hair clumping, mild itch, or redness at the application site.
• Gastrointestinal signs such as vomiting, soft stool, or decreased appetite.
• Drooling, lip smacking, or transient agitation, especially if the product is licked before drying.
• Lethargy or hiding for a short period after application.

Serious reactions are uncommon but can include marked skin irritation, persistent vomiting, neurologic signs (tremors, incoordination), or signs of allergy. Product is for cats only and not for human use. Prevent contact with the application site until dry; ingestion can increase adverse effects. Seek veterinary attention for concerning or persistent symptoms.

Drug Interactions and Cautions

There are no widely reported major drug interactions for emodepside/praziquantel in healthy cats, but caution is prudent when combining dewormers or multiple topical parasiticides on the same day. A clinician may avoid concurrent use with other macrocyclic lactone spot‑ons or with drugs that significantly affect P‑glycoprotein transport. When year‑round coverage is needed, consider integrated options such as Nexgard Combo, and use only one topical parasite product at a time unless a veterinarian directs otherwise. Separate applications of different topicals by at least a day unless a clinician provides a tailored plan.

What to Expect Over Time

After application, intestinal worms begin to die, and segments may be seen transiently in stool or near the anus, particularly with tapeworms. Most cats show no change in behavior beyond brief grooming avoidance. In environments with fleas or prey exposure, periodic fecal checks help confirm clearance. Pairing deworming with monthly flea control, such as Revolution For Cat, lowers the chance of new tapeworm exposure. In mixed‑pet homes, dogs may also need their own parasite control, for example Revolution For Dog, as advised by a clinician. For background reading on tapeworm treatment, see Droncit For Cats. Expectations should remain flexible; reinfection can occur in active or outdoor cats, and prevention reduces the need for repeat treatments.

Compare With Alternatives

Two commonly used alternatives include:

• Drontal: oral tablets that treat roundworms, hookworms, and tapeworms; suited to cats comfortable with pills.
• Revolution Plus: topical parasiticide for cats that adds broad ectoparasite and some endoparasite coverage; typically used monthly for prevention.

Choice depends on a cat’s temperament, exposure risks, and a clinician’s assessment. Profender provides single‑dose intestinal coverage without the need to pill a cat, while monthly preventives may be preferred when combined flea, tick, and mite protection is a priority.

Pricing and Access

Ordering Profender through CanadianInsulin offers access to Canadian pricing with US delivery from Canada. Many clients find meaningful cash‑pay savings compared with local clinic retail, especially when purchasing multiple tubes for multi‑cat homes or seasonal parasite control. Orders ship with prompt, express, cold‑chain shipping. Checkout and customer data are protected by encrypted transfer.

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Availability and Substitutions

Supply can vary by package size and weight band. If a specific presentation is unavailable, a prescriber may recommend a suitable alternative based on the cat’s weight and parasite risk, such as a tablet dewormer or a monthly topical preventive. Availability may shift seasonally; pharmacists can dispense an equivalent package size when appropriate and approved by the prescriber.

Patient Suitability and Cost‑Saving Tips

• Best for cats that resist oral tablets or live in environments with ongoing exposure risks.
• Not intended for cats below the labeled age and weight thresholds.
• In multi‑cat households, weigh each pet and select the correct tube size for every cat.
• Ordering a multi‑month supply can reduce per‑dose costs and help maintain continuity.
• Set refill reminders based on planned fecal testing intervals or seasonal exposure patterns.
• Combine deworming with consistent flea control to limit reinfection risk and unnecessary repeat dosing.
• Confirm current weight before each application to avoid under‑ or overdosing.

Questions to Ask Your Clinician

• Does this cat’s age and weight match the correct Profender tube size?
• How often should fecal testing be performed after treatment to confirm clearance?
• Should this household also use flea control such as Revolution Plus to prevent tapeworm reinfection?
• When is it appropriate to repeat Profender, and what interval should be observed?
• How long should grooming or bathing be restricted after application?
• Are there medical conditions or medications that would make a different dewormer preferable?

Authoritative Sources

• Elanco Profender overview
• CAPC roundworm guidelines
• CAPC tapeworm guidelines

Ready to secure Profender for your cat? Place an order with CanadianInsulin for US delivery from Canada and prompt, express, cold‑chain shipping.

Disclaimer: This information is educational and not a substitute for professional veterinary advice. Always follow the prescribing veterinarian’s directions and the product label.