Shop now & save up to 80% on medication

New here? Get 10% off with code WELCOME10
Promotion
Profender

Profender® Topical Solution for Cats

Please note: a valid prescription is required for all prescription medication.

Sitewide Super Sale - Get 15% off when you buy 3 or more of the same product using the code LESS15 at checkout.
Applies to all products originating from Canada. Maximum quantity limited to a 90-day supply per order.

Black Friday Bonus - Spend $700 or more and get an extra $50 off at checkout with the code PLUS50.
Can be combined with the Sitewide Super Sale.
Enter each coupon code separately at checkout. Offer ends December 5, 2025.
Price:

Price range: $40.99 through $348.99
You save

Total:
Each:

Profender is a spot-on dewormer for cats that treats common intestinal worms. This guide covers how the treatment works, safety basics, and how to use it effectively with US shipping from Canada, even if paying without insurance.

What Profender Is and How It Works

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

Profender® combines two actives: emodepside and praziquantel. Emodepside targets roundworms and hookworms by affecting parasite neuromuscular function. Praziquantel disrupts tapeworm integrity, causing paralysis and death. Together, this medicine treats Toxocara cati, Ancylostoma tubaeforme, Dipylidium caninum, and Taenia taeniaeformis. The phrase emodepside praziquantel for cats often refers to this broad-spectrum combination.

The treatment is applied to the skin at the base of the skull. It absorbs through the skin and enters systemic circulation. Activity against susceptible parasites occurs after absorption according to the labeled mechanism.

Who It’s For

This topical treatment is indicated for cats and kittens at least 8 weeks of age and weighing 2.2 lb (1 kg) or more. Do not use on cats that are under the minimum age or weight. The safety of use in breeding, pregnant, or lactating queens has not been established; a veterinarian may advise alternative timing. Avoid use in animals with known sensitivity to the components. Do not use on visibly ill or debilitated animals unless a veterinarian determines the benefit outweighs risk.

Dosage and Usage

Use a single dose based on body weight. Select the correct tube size for the cat’s weight range. Part the hair at the base of the skull and apply the full contents directly to the skin. Keep the application area dry and out of reach of grooming until dry. Prevent other pets from licking the site. Wash hands after handling, and keep children away from the application site until it is dry. For label-specific details, consult the Profender for cats dosage guide and follow veterinary directions. To explore related items, see Pet Medications.

Strengths and Forms

Available as Profender Topical Solution for Cats in single-use tubes. Presentations generally correspond to weight bands for small, medium, and large cats.

  • Small cats: tube sized for approximately 2.2 to 5.5 lb
  • Medium cats: tube sized for approximately >5.5 to 11 lb
  • Large cats: tube sized for approximately >11 to 17.6 lb

Availability can vary by pharmacy and region. Packaging includes foil pouches and child-resistant features.

Missed Dose and Timing

If a scheduled deworming dose was missed or timing is uncertain, ask a veterinarian for guidance before reapplying. Do not apply an additional tube on the same day to make up for uncertainty. Avoid bathing immediately around application; follow the product label regarding water exposure. Keep cats separated until the site has dried to reduce licking. In multi-cat homes, observe for grooming behavior and redirect if needed.

Storage and Travel Basics

Store at room temperature as directed on the label and protect from excessive heat. Keep the tube in its original pouch until use. Avoid puncture or crushing. Keep out of reach of children and other animals. When traveling, carry tubes in a sealed bag with the prescription copy, and store away from direct sun. For flights, keep medicine in a carry-on to avoid temperature extremes. Some items require temperature-controlled handling when required; follow the label and pharmacy instructions.

Benefits

This treatment provides broad-spectrum control of intestinal parasites in a single topical dose. It avoids oral tablets, which may be challenging for some cats. Weight-banded packaging simplifies selection. The application site at the base of the skull helps limit self-grooming exposure. The therapy can support routine parasite control programs when directed by a veterinarian.

Side Effects and Safety

Common Profender for cats side effects may include temporary hair loss, mild skin irritation at the application site, scratching, or transient lethargy. If a cat licks the application area before it dries, drooling or gagging can occur due to taste, not toxicity. Occasional vomiting or soft stool may be observed.

  • Application site irritation
  • Transient drooling if licked
  • Occasional vomiting
  • Restlessness or hiding

Serious reactions are uncommon but can include allergic responses or neurological signs if a large amount is ingested. Human exposure should be avoided; if contact occurs, wash thoroughly. Keep the product away from children. Seek veterinary care promptly if severe or persistent signs develop. Always read the label prior to use.

Drug Interactions and Cautions

Use caution when combining with other dewormers or parasite control products unless a veterinarian advises otherwise. The combination emodepside praziquantel spot-on for cats has not shown widespread interactions, but professional oversight helps avoid duplication or unintended exposure. Do not apply on broken or irritated skin. If the household includes sensitive individuals or pregnant people, minimize contact with the application site until fully dry. For broader pet care reading, see Pet Antibiotic Guide.

What to Expect Over Time

After application, susceptible intestinal worms are targeted according to the label. Some cats may pass visible tapeworm segments. Litter box hygiene helps reduce reinfection. Veterinarians may recommend fecal testing at intervals to monitor for parasites. In regions with high parasite pressure, integrated control that addresses fleas and intermediate hosts may be advised. Maintain routine wellness checks to align deworming with the cat’s risk profile. For context on veterinary prescribing, you can review Cat Medicine Uses and Allergic Skin Relief.

Compare With Alternatives

For broader parasite control including fleas, ticks, and some intestinal worms, a veterinarian may consider Revolution® Plus. For tapeworms and certain roundworms in tablet form, another option is Drontal®. Choice depends on parasite risk, tolerance of topical vs oral forms, and the cat’s medical profile.

Pricing and Access

Canadian pharmacy options can offer competitive pricing with US shipping from Canada. You can compare sizes and see current options before checkout. Many pet owners consider buy emodepside praziquantel topical for cats when preferring a single-dose approach. Review available tubes and confirm the correct weight band with a prescription. To see current offers, visit Promotions. Check pricing details on the product page and discuss overall costs with your veterinarian as part of your parasite control plan.

Availability and Substitutions

Supply can vary by location and season. If a selected tube size is temporarily unavailable, a prescriber may recommend a suitable alternative based on the same therapeutic goals. Some customers search for Profender for cats from Canada when local stock is limited. Do not switch to a different dewormer without veterinary guidance, as coverage and spectra differ across products.

Patient Suitability and Cost-Saving Tips

Cats meeting the age and weight minimums, and without known hypersensitivity to the components, may be candidates. Cats with skin issues at the application site may need alternative plans. To manage expenses, consider multi-month planning for deworming schedules and set refill reminders before travel. Discuss household risks, indoor-outdoor status, and flea control to reduce re-treatment needs. If paying out of pocket, compare pricing across tube sizes and confirm the correct weight band to avoid waste.

Questions to Ask Your Clinician

  • Which parasites are most likely in my region and household?
  • Is a topical dewormer suitable for my cat’s age and weight?
  • How should I separate pets after application to prevent licking?
  • When should I recheck a fecal sample after treatment?
  • Can this product be coordinated with flea control safely?
  • What signs would require stopping and contacting the clinic?
  • How should I plan dosing if my cat’s weight changes?

Authoritative Sources

Ready to proceed? Place your order with prompt checkout and US shipping from Canada. Always follow prescription directions and the product label.

Disclaimer: This information is educational and not a substitute for veterinary advice. Consult a veterinarian for diagnosis, treatment decisions, and individualized guidance.

Express Shipping - from $25.00

Shipping with this method takes 3-5 days

Prices:
  • Dry-Packed Products $25.00
  • Cold-Packed Products $35.00

Standard Shipping - $15.00

Shipping with this method takes 5-10 days

Prices:
  • Dry-Packed Products $15.00
  • Not available for Cold-Packed products

Rewards Program

Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.

You can read more about rewards here.

POINT VALUE

100 points
1 USD

How to earn points

  • 1Register and/or Login
    Create an account and start earning.
  • 2Earn Rewards
    Earn points every time you shop or perform certain actions.
  • 3Redeem
    Redeem points for exclusive discounts.

You Might Also Like

Promotion
Zycortal

$306.99
You save

  • In Stock
  • Express Shipping
Select options This product has multiple variants. The options may be chosen on the product page
Promotion
Vyzulta Ophthalmic Solution

$77.99
You save

  • In Stock
  • Express Shipping
Select options This product has multiple variants. The options may be chosen on the product page
Promotion
Vincristine

$64.99
You save

  • In Stock
  • Express Shipping
Select options This product has multiple variants. The options may be chosen on the product page
Promotion
Vetmedin

Price range: $87.99 through $123.99
You save

  • In Stock
  • Express Shipping
Select options This product has multiple variants. The options may be chosen on the product page

Related Articles

Weight Loss
Zepbound Storage: How to Keep It Safe and Effective

Zepbound (tirzepatide) is a major advancement in chronic weight management. This once-weekly injection works best when stored and handled properly. Temperature, light exposure, and how long it stays out of…

Read More
Weight Loss
Zepbound and Fatigue: Simple Ways to Feel Better

Starting a new weight loss medication like Zepbound can be exciting, especially if it promises lasting results. But for many patients, Zepbound and fatigue seem to go hand in hand,…

Read More
Cardiovascular Health, Diabetes,
Mounjaro Heart Benefits That Go Beyond Weight Loss

Weight loss often steals the spotlight when people talk about Mounjaro, but the story doesn’t end there. Did you know that cardiovascular disease remains the leading cause of death for…

Read More
Weight Loss
Ozempic Rebound: How to Prevent Weight Regain

Weight loss with medications like Ozempic has become a life-changing experience for many. People who struggled for years to lose weight are finally seeing results: lower numbers on the scale,…

Read More