Are Diabetics Immunocompromised?

Are diabetics immunocompromised? The term “immunocompromised” refers to a condition where an individual’s immune system is not working properly in tandem with the rest of the body. This condition can happen for a variety of reasons, and one of them includes pre-existing or underlying medical conditions.

HIV and Diabetics

One of the best examples of an immunocompromised state is HIV infection. Since HIV infects the CD4 cells or T cells, the immune system weakens. The presence of HIV in these types of white blood cells makes it a struggle to fight further infection and illnesses. But how about diabetes? Are people with varying blood sugar levels immunocompromised?

A person diagnosed with diabetes does not necessarily have an immunocompromised status. However, most people with high or low blood glucose levels have compromised immune systems. Does an immunocompromised status apply to people with type 1 diabetes?

If you have been diagnosed with type 1 diabetes, you are not considered immunocompromised. Regardless of it being an autoimmune disease, the term immunocompromised is not related to type 1 diabetes. However, an immunocompromised status can occur if you have been following certain medications that slow down your immune system’s functions.

People become more prone to infections or diseases when they are immunocompromised. This is mainly because their immune system’s efficiency is being reduced.

Dr. Bernard Khor, an immunologist from Benaroya Research Institute at Virginia Mason (BRI), stated that people with autoimmune diseases, such as type 1 diabetes, are more immune dysregulated than immunocompromised.

What does immune dysregulated mean?

It is a health status where the immune system is not functioning properly because of a particular medical condition that influences the body adversely. For example, in people with type 1 diabetes, their pancreas receives the most damage. However, this does not mean that they cannot fight other infections in the future.

Takeaway

Technically, people with diabetes are not considered immunocompromised. Having an immunocompromised status means being susceptible to future infections and not being able to manage or fight them properly. On the other hand, those with varying blood sugar levels may still be at risk of developing complications. Still, their immune system is very much capable of preventing and managing them.

Doctor’s Recommendation

Take proactive steps to be among the 5% of diabetics with a healthy immune system. This means aiming for a target glycated hemoglobin (HbA1c) of approximately 4.5% to 5.3%, similar to that of a healthy non-diabetic individual. While doctors typically recommend a target HbA1c of 6-7%, achieving optimal glycemic control requires diligent and regular glucose monitoring and precisely calculated insulin dosages, as the risk of hypoglycemia increases with small miscalculations.

Strive to gradually approach this ideal target, ensuring you are prepared for the long-term challenge. Patients should discuss with their primary care physician (PCP) their desire to take on more responsibility and the associated risks, balanced by discipline and commitment.