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Synjardy Side Effects

How to Recognize and Address Synjardy Side Effects

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Summary: Synjardy is commonly used to manage Type 2 diabetes by improving blood sugar control. While it is effective, it may cause side effects such as nausea, UTIs, and yeast infections. Managing  Synjardy side effects with proper hydration, diet, and medical consultation is key to successful treatment.

While it can be highly effective, Synjardy, like any medication, can come with certain side effects. Synjardy is a combination medication containing empagliflozin and metformin, commonly prescribed for managing Type 2 diabetes. 

In this article, we’ll explore the common and less common Synjardy side effects, as well as ways to address them for better treatment outcomes.

Understanding Synjardy: How It Works and What It Does

Synjardy is a combination drug used to control blood sugar levels in individuals with Type 2 diabetes. It combines two medications: empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and metformin, a biguanide. Empagliflozin helps the kidneys excrete excess glucose, while metformin works by increasing the body’s sensitivity to insulin, leading to better glucose utilization. 

For some patients, Synjardy weight loss can be an added benefit, offering support not only for blood sugar control but also for managing excess weight as part of their diabetes treatment plan.

While Synjardy is generally effective in lowering blood sugar, its use may come with a variety of side reactions, ranging from mild to severe. Knowing what to expect and how to address these side reactions is important for patients using this medication. 

Common Side Effects of Synjardy

Most people taking Synjardy will experience some side effects, though they are typically mild and improve with time. Recognizing these early signs can help individuals and their healthcare providers address them appropriately.

Gastrointestinal Issues

One of the most common Synjardy side effects is gastrointestinal distress. This encompasses symptoms such as nausea, diarrhea, and abdominal discomfort. These issues can arise when starting the medication or after an increase in dosage.

To manage these side effects, it’s recommended to take Synjardy with food. This can help reduce gastrointestinal discomfort. 

Urinary Tract Infections (UTIs)

Due to the effects of empagliflozin on the kidneys, some people may experience urinary tract infections (UTIs) as a side effect. These can include symptoms, including frequent urination, pain or inflammation during urination, and cloudy or strong-smelling urine.

To prevent UTIs, it’s important to stay hydrated and maintain good hygiene. If a UTI does develop, prompt treatment with antibiotics is necessary. 

Yeast Infections

Another common side effect associated with Synjardy is an increased risk of yeast infections. The glucose-lowering action of empagliflozin increases glucose in the urine, which may create an environment where yeast can thrive. This can lead to vaginal or penile yeast infections.

Maintaining proper hygiene and using antifungal treatments can help prevent and address yeast infections. Patients should inform their doctor if they experience symptoms like itching, redness, or unusual discharge, as these may indicate a yeast infection.

Serious Side Effects of Synjardy

While the common side effects of Synjardy are generally manageable, there are more serious side effects that require immediate attention. Although rare, it’s crucial to recognize these and seek medical help right away.

Lactic Acidosis

A rare but potentially life-threatening side effect of metformin, one of the components of Synjardy, is lactic acidosis. This condition occurs when there is a buildup of lactic acid in the blood, which can lead to symptoms like dizziness, muscle pain, fatigue, difficulty breathing, and a slow or irregular heartbeat.

Lactic acidosis requires immediate medical attention and may necessitate discontinuing the medication. Individuals at higher risk for this condition, such as those with kidney problems, should be closely monitored by their healthcare provider.

Dehydration and Low Blood Pressure

Due to empagliflozin’s action on the kidneys, Synjardy can trigger dehydration and a drop in blood pressure. Symptoms of dehydration encompass excessive thirst, dry mouth, dizziness, and lightheadedness, particularly when standing up.

To minimize the risk of dehydration, it’s essential to drink plenty of fluids while taking Synjardy. If symptoms of dehydration or low blood pressure occur, it’s important to contact a healthcare provider immediately. 

Kidney Issues

Both components of Synjardy can affect kidney function. While empagliflozin works on the kidneys to remove excess glucose, it can also cause kidney-related side effects in some patients. Monitoring kidney function is essential for those taking this medication, especially those with existing kidney conditions.

If any signs of kidney dysfunction develop, such as swelling in the legs or ankles, changes in urine output, or difficulty urinating, patients should stop taking Synjardy and seek medical care immediately.

Managing and Addressing Synjardy Side Reactions

Understanding how to manage the side effects of  Synjardy is key to ensuring the medication’s success in managing Type 2 diabetes while maintaining quality of life.

Regular Monitoring

Patients taking Synjardy should have regular check-ups with their healthcare provider to monitor blood sugar levels, kidney function, and overall health. This helps ensure the medication is working effectively and allows any side effects to be addressed early.

Adjusting Dosages

For some individuals, adjusting the dosage of Synjardy can help reduce side effects. If gastrointestinal issues persist, a healthcare provider may recommend lowering the dose or switching to a different treatment. Similarly, if side effects like UTIs or yeast infections are frequent, discussing alternatives with the doctor is important.

Lifestyle Modifications

In addition to taking Synjardy, adopting healthy lifestyle changes can help manage side effects and improve overall treatment outcomes. Maintaining a balanced diet, staying hydrated, and engaging in regular physical activity can lessen the risk of side effects like dehydration, weight gain, and infections.

When to Seek Medical Attention

Patients should seek medical attention if they experience any of the following serious side effects of Synjardy:

  • Symptoms of lactic acidosis (muscle pain, breathing difficulties, dizziness)
  • Severe dehydration or low blood pressure (lightheadedness, fainting)
  • Signs of kidney problems (swelling, changes in urine output)
  • Unexplained weight loss or persistent nausea

Timely medical intervention can help prevent complications and ensure the safety and effectiveness of Synjardy treatment.

Takeaways

Synjardy side effects can range from mild gastrointestinal discomfort to more serious conditions like lactic acidosis and kidney problems. 

The most common side effects are nausea, diarrhea, UTIs, and yeast infections, but these can often be managed through proper hydration, hygiene, and dosing adjustments.

Serious side effects, including dehydration and kidney issues, should be addressed at once with a healthcare provider. Regular monitoring and lifestyle changes are vital in managing these side effects. If symptoms of lactic acidosis or other severe reactions occur, seek immediate medical help to avoid complications.

By understanding and addressing the side effects of  Synjardy, patients can better manage their treatment and optimize their diabetes control with minimal discomfort.

Frequently Asked Questions (FAQs) 

What are the most common side effects of Synjardy?

The most common side effects of Synjardy include gastrointestinal issues like nausea, diarrhea, and abdominal discomfort, as well as urinary tract infections and yeast infections.

How can I manage the side effects of Synjardy?

Managing side effects of Synjardy includes taking the medication with food, staying hydrated, maintaining good hygiene, and consulting your healthcare provider for dosage adjustments if needed.

When should I contact my healthcare provider about side effects?

If you experience any serious side effects, such as symptoms of lactic acidosis, dehydration, kidney problems, or persistent infections, contact your healthcare provider immediately for evaluation and treatment. 

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Written by CDI Staff Writer on December 13, 2024

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